Yes it is very possible. Could you be more specific in where you are having trouble?

Nate

well, in m4l i choose a plugin~ to audio in and midiout for...midi out but i can't put a external synthesizer next to my m4l patch (ex. operator) in chain so it can receive midi...

m4l audio devices can't have midi output. It's a limitation imposed by Live. But you can transmit midi via send/receive to a m4l midi device on another track where the synthesizer is on. However, timing is not perfect (latency dependent on Live's audio buffer size).

Ok, i'll try that way...thanks for the help.

Cheers

You could try sending the MIDI out to MIDIYoke or something similar and then back into Ableton. Alternately have a look at http://koen.smartelectronix.com/KTDrumTrigger/ - it's easy to use and give 3 triggers.